Ik denk dat onderstaand onderzoek uit 2010 als basis voor de taurinevragen hebben geleid. Interessant onderzoekje, en na het lezen van dit onderzoek ben ik gestart met 500mg. Heb wel even pubmed er op na geslagen of ik dit veilig kon gaan gebruiken.
effect of supplemental dietary taurine on tinnitus and auditory discrimination in an animal model.
Brozoski TJ, Caspary DM, Bauer CA, Richardson BD.
Division of Otolaryngology, Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA. email@example.com
Loss of central inhibition has been hypothesized to
underpin tinnitus and impact auditory acuity. Taurine,
a partial agonist at inhibitory glycine and γ-amino butyric
acid receptors, was added to the daily diet of rats to
examine its effects on chronic tinnitus and normal
auditory discrimination. Eight rats were unilaterally
exposed once to a loud sound to induce tinnitus.
The rats were trained and tested in an operant
task shown to be sensitive to tinnitus. An equivalent
unexposed control group was run in parallel. Months
after exposure, 6 of the exposed rats showed significant
evidence of chronic tinnitus. Two concentrations of taurine
in drinking water were given over several weeks (attaining
average daily doses of 67 mg/kg and 294 mg/kg). Water
consumption was unaffected. Three main effects were
obtained: (1) The high taurine dose significantly attenuated
tinnitus, which returned to near pre-treatment levels
following washout. (2) Auditory discrimination was significantly
improved in unexposed control rats at both doses. (3)
As indicated by lever pressing, taurine at both doses had a
significant group-equivalent stimulant effect. These results
are consistent with the hypothesis that taurine attenuates
tinnitus and improves auditory discrimination by increasing
inhibitory tone and decreasing noise in the auditory pathway.
Copyright © 2010 Elsevier B.V. All rights reserved.
PMID: 20868734 [PubMed - indexed for MEDLINE] PMCID: PMC2997922 [Available on 2011/12/1]